Contribution of LILRB1 polymorphism and HLA-DRB1-shared epitope to rheumatoid arthritis

JFD De La Poza, E Cantó, C Díaz-Torné, BF Villahoz… - Inmunología, 2011 - Elsevier
Objectives The LILRB1 gene has recently been associated with rheumatoid arthritis (RA)
susceptibility in HLA-DRB1-shared epitope (SE) negative Japanese individuals. Since the
contribution of the LILRB1 polymorphism to RA susceptibility may vary among ethnic
populations, we examined this association in a group of Caucasian patients. The frequency
of LILRB1 alleles was also determined in patients according to the presence of DRB1-SE.
Methods Samples from 103 RA patients and 107 healthy controls were randomly collected …

Contribution of LILRB1 polymorphism and HLA-DRB1-shared epitope to rheumatoid arthritis.

JFD Poza, E Cantó, C Díaz-Torné, BF Villahoz… - 2011 - cabidigitallibrary.org
Objectives: The LILRB1 gene has recently been associated with rheumatoid arthritis (RA)
susceptibility in HLA-DRB1-shared epitope (SE) negative Japanese individuals. Since the
contribution of the LILRB1 polymorphism to RA susceptibility may vary among ethnic
populations, we examined this association in a group of Caucasian patients. The frequency
of LILRB1 alleles was also determined in patients according to the presence of DRB1-SE.
Methods: Samples from 103 RA patients and 107 healthy controls were randomly collected …