The predominant form of life for the majority of microorganisms in any hydrated biologic
system is a cooperative community termed a “biofilm.” A biofilm on an indwelling urinary
catheter consists of adherent microorganisms, their extracellular products, and host
components deposited on the catheter. The biofilm mode of life conveys a survival
advantage to the microorganisms associated with it and, thus, biofilm on urinary catheters
results in persistent infections that are resistant to antimicrobial therapy. Because chronic …