Publisher Summary The three-dimensional structures of more than 20 representatives of the
α/β hydrolase fold are now known and many more members have been identified by
sequence and secondary structure comparisons. The fold is proving to be a common and
stable way to assemble a wide variety of catalytic activities. With emphasis on lipases, this
chapter reviews the features of this fold and the resources used to identify similarities in the
rapidly growing number of enzymes and proteins that share this fold. The enzymes in this …