miR-221 alleviates the inflammatory response and cell apoptosis of neuronal cell through targeting TNFAIP2 in spinal cord ischemia–reperfusion

D Zhao, SC Deng, Y Ma, YH Hao, ZH Jia - Neuroreport, 2018 - journals.lww.com
This study aimed to examine the role of miR-221 in inflammatory response and apoptosis of
neuronal cells after spinal cord ischemia/reperfusion (I/R) injury. Blood samples were
obtained from 20 I/R patients and that of 20 healthy individuals were used as a control.
AGE1. HN and SY-SH-5Y neuronal cell lines subjected to oxygen–glucose deprivation
(OGD) stress were used in cell experiments. Real-time PCR and western blot were used to
evaluate the expression of miR-221, tumor necrosis factor-α, and TNFAIP2. TUNEL assay …