[HTML][HTML] The role of reactive oxygen species (ROS) in persistent pain
JM Chung - Molecular interventions, 2004 - triggered.edina.clockss.org
Pain is an important medical problem and has been the subject of intense study in recent
years; however, we still do not understand many of the details of pain generation and
analgesic mechanisms, particularly for persistent pain. This lack of sufficient understanding
is a major stumbling block in the development of much better analgesic drugs.We now know
that the mechanisms of chronic or persistent pain (such as pain associated with
inflammation or nerve injury) are fundamentally different from those of acute pain …
years; however, we still do not understand many of the details of pain generation and
analgesic mechanisms, particularly for persistent pain. This lack of sufficient understanding
is a major stumbling block in the development of much better analgesic drugs.We now know
that the mechanisms of chronic or persistent pain (such as pain associated with
inflammation or nerve injury) are fundamentally different from those of acute pain …
